Hydatidiform mole

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Hydatidiform mole

ORPHA:99927Disease

Also called Molar pregnancy

What it is

A rare, benign gestational trophoblastic disease that develops during pregnancy and is characterized by the abnormal fertilization, trophoblastic proliferation, and abnormal or absent embryo development. Hydatidiform moles can be either complete or partial.

Key facts

Age of onset
Adolescent, Adult
Inheritance
Autosomal recessive, Not applicable
Classified as
Disease

Signs and symptoms

These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.

Genes reported in subtypes

KHDC3LMEI1NLRP7TOP6BL

Orphanet records these genes on 2 more specific entries under this disorder, not on this entry itself:

A well-studied disease is usually split into subtypes, and the gene is curated on whichever one the evidence belongs to. Open a subtype to see which gene goes with it.

ICD-10 codes

O01.0ICD-10 uses a narrower term — shared with 1 other rare disease
O01.1ICD-10 uses a narrower term — shared with 1 other rare disease
O01.9ICD-10 uses a narrower term

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Cross-references

GARD 10263MEDDRA 10020481MESH D006828MONDO 0006248OMIM 231090OMIM 614293UMLS C0020217

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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