Rare diseases · Sign or symptom

Medullary nephrocalcinosis

HP:0012408

What it means

The deposition of calcium salts in the parenchyma of the renal medulla (innermost part of the kidney).

Rare diseases that can present with this3

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Medullary nephrocalcinosis

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.