Rare diseases · Sign or symptom
Inflammation of the large intestine
HP:0002037
What it means
Inflammation, or an inflammatory state in the large intestine.
Rare diseases that can present with this26
Common30–79%
6Sometimes5–29%
13- Alopecia totalis
- Autoimmune hepatitis
- Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsuffiency
- Chronic nonbacterial osteomyelitis/Chronic recurrent multifocal osteomyelitis
- Epidermolysis bullosa acquisita
- Glycogen storage disease due to glucose-6-phosphatase deficiency type Ib
- Kindler epidermolysis bullosa
- Linear IgA dermatosis
and 5 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Inflammatory bowel disease
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.