Rare diseases · Sign or symptom

Hyperplasia of the maxilla

Big maxilla

HP:0430028

What it means

Abnormally increased dimension of the maxilla, especially relative to the mandible, resulting in a malocclusion or malalignment between the upper and lower teeth or in anterior positioning of the nasal base, increased convexity of the face, increased nasolabial angle, or increased width (transverse dimension of the maxilla.

Rare diseases that can present with this10

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Big upper jaw · Hyperplasia of upper jaw · Hypertrophy of maxilla · Hypertrophy of upper jaw · Increased projection of maxilla · Increased projection of upper jaw · Increased size of maxilla · Increased size of upper jaw

Hyperplasia of the maxilla

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.