Rare diseases · Sign or symptom

Hyperostosis frontalis interna

HP:0004438

What it means

Bony overgrowth of the internal (endosteal) surface of the frontal bone.

Rare diseases that can present with this3

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Enlargement of the inner surface of the frontal bone · Excessive growth of inner surface of the frontal bone · Hyperostosis of the internal surface of the frontal bone · Hypertrophy of the internal surface of the frontal bone · Increased ossification of the internal surface of the frontal bone · Overgrowth of the inner surface of the frontal bone · Overgrowth of the inside of the frontal bone · Thick inner surface of the frontal bone

Hyperostosis frontalis interna

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.