Rare diseases · Sign or symptom
Cranial hyperostosis
HP:0004437
What it means
Excessive growth of the bones of cranium, i.e., of the skull.
Rare diseases that can present with this8
Very common80–99%
4Sometimes5–29%
2The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Enlargement of skull bones · Excessive growth of skull bones · Hyperostosis of cranial bones · Hyperostosis of cranial vault · Hypertrophy of cranial bones · Increased ossification of cranial bones · Overgrowth of skull bones · Thick skull bones
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.