Rare diseases · Sign or symptom
Hyperglycemia
High blood sugar
HP:0003074
What it means
An increased concentration of glucose in the blood.
In everyday care
Most people with this sign do not have a rare disease — it appears in common conditions far more often. These general reference pages cover the same topic:
Rare diseases that can present with this16
Very common80–99%
5Sometimes5–29%
8- Acquired aneurysmal subarachnoid hemorrhage
- Beta-ketothiolase deficiency
- Cognitive impairment-coarse facies-heart defects-obesity-pulmonary involvement-short stature-skeletal dysplasia syndrome
- Hereditary pheochromocytoma-paraganglioma
- Necrotizing enterocolitis
- Pyruvate carboxylase deficiency
- Scorpion envenomation
- Sporadic pheochromocytoma/secreting paraganglioma
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions, and Orphanet separately records 3 diseases where this sign is specifically absent. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: High blood glucose
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.