Rare diseases · Sign or symptom

Hemifacial hypertrophy

Enlargement of half of face

HP:0005323

What it means

Unilateral overgrowth of facial tissues, including muscles, bones and skin.

Rare diseases that can present with this1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Facial hemihyperplasia · Facial hemihypertophy · Friedreich's disease · Hemifacial enlargement · Hypertrophy of half of face · Increase in size of half of face · Overgrowth of half of face

Hemifacial hypertrophy

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.