Rare diseases · Sign or symptom

Focal motor seizure

HP:0011153

What it means

A type of focal-onset seizure characterized by a motor sign as its initial semiological manifestation.

A motor onset seizure involves motor activity (movement) and may be due to either an increase or decrease in contraction in a muscle or group of muscles. Depending on the muscle groups involved and the way they are affected, the movement features of a motor onset seizure may be simple or more complex.

Rare diseases that can present with this20

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Focal motor seizures · Localised motor seizure · Localised motor seizures · Localized motor seizure · Localized motor seizures · Partial motor seizure · Partial motor seizures · Segmental motor seizure

Focal motor seizure

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.