Rare diseases · Sign or symptom
Delayed closure of the anterior fontanelle
Later than typical closing of soft spot of skull
HP:0001476
What it means
A delay in closure (ossification) of the anterior fontanelle, which generally undergoes closure around the 18th month of life.
Rare diseases that can present with this7
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Delayed closure anterior fontanel · Delayed closure of anterior fontanelle · Delayed closure of the bregma sutures · Delayed closure of the soft spot on the skull · Late closure of anterior fontanelle · Late closure of large anterior fontanel · Late closure of soft spot on the skull · Late closure of the bregma sutures
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.