Decreased circulating ceruloplasmin concentration

What it means

The concentration of ceruloplasmin in the blood circulation is below the lower limit of normal.

Ceruloplasmin is the major copper-carrying protein in the serum. Decreased serum ceruloplasmin levels can indicate other defects in copper metabolism.

Rare diseases that can present with this4

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions, and Orphanet separately records 1 disease where this sign is specifically absent. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Decreased ceruloplasmin concentration · Decreased ceruloplasmin level · Decreased ceruloplasmin level in blood · Decreased serum ceruloplasminA · Hypoceruloplasminaemia · Hypoceruloplasminemia · Reduced ceruloplasmin concentration · Reduced ceruloplasmin level