Rare diseases · Sign or symptom
Clinodactyly
Permanent curving of the finger
HP:0030084
What it means
An angulation of a digit at an interphalangeal joint in the plane of the palm (finger) or sole (toe).
Rare diseases that can present with this62
Common30–79%
20- 21q22.11q22.12microdeletion syndrome
- 6p22microdeletion syndrome
- Antenatal multiminicore disease with arthrogryposis multiplex congenita
- Coffin-Siris syndrome
- Distal deletion 10q syndrome
- Distal Xq28 microduplication syndrome
- Fibrodysplasia ossificans progressiva
- Growth delay due to insulin-like growth factor I resistance
- Growth delay due to insulin-like growth factor type 1 deficiency
- Maternal uniparental disomy of chromosome 20 syndrome
- Oculodentodigital dysplasia
- Ring chromosome 12 syndrome
- Ring chromosome 15 syndrome
- Ring chromosome 3 syndrome
- Short ulna-dysmorphism-hypotonia-intellectual disability syndrome
- Silver-Russell syndrome due to maternal uniparental disomy of chromosome 7
- Symphalangism with multiple anomalies of hands and feet
- TELO2-related intellectual disability-neurodevelopmental disorder
- Terminal osseous dysplasia-pigmentary defects syndrome
- XYLT1-CDG
Sometimes5–29%
37- 15q24microdeletion syndrome
- 19p13.13microdeletion syndrome
- 19p13.3microduplication syndrome
- 20p13microdeletion syndrome
- 6q terminal deletion syndrome
- Autosomal recessive spastic paraplegia type 20
- Basel-Vanagaite-Smirin-Yosef syndrome
- Classical-like Ehlers-Danlos syndrome type 1
and 29 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Curvature of digit
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.