Rare diseases · Sign or symptom
Chronic decreased circulating IgA concentration
HP:0003460
What it means
Undetectable serum immunoglobulin A level at a value < 5 mg/dL (0.05 g/L).
Rare diseases that can present with this3
Common30–79%
2The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Decreased total IgA in blood · Total immunoglobulin A deficiency
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.