Rare diseases · Sign or symptom

Anti-nucleoporin 62 antibody positivity

HP:0033556

What it means

The presence of autoantibodies (immunoglobulins) in the serum that react against nucleoporin 62.

Anti-nucleoporin 62 antibody is an antibody directed against components of the nuclear membrane and is typically found in primary biliary cirrhosis.

Rare diseases that can present with this1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Anti-p62 antibody positivity

Anti-nucleoporin 62 antibody positivity

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.