Rare diseases · Sign or symptom
Abnormal temper tantrums
HP:0025160
What it means
Temper tantrums are brief episodes of extreme, unpleasant, and sometimes aggressive behaviors in response to frustration or anger, which are a normal part of development in toddlers. Temper tantrums that occur more frequently in a given time and/or are more severe in symptomatology and/or longer in duration and/or inappropriate for the given age compared to a temper tantrum that naturally occurs as a part of the developmental process are classified as abnormal temper tantrums.
Rare diseases that can present with this27
Very common80–99%
2Common30–79%
12- 6q16microdeletion syndrome
- Helsmoortel-Van der Aa syndrome
- Houge-Janssens syndrome type 1
- Prader-Willi syndrome due to maternal uniparental disomy of chromosome 15
- Prader-Willi syndrome due to paternal 15q11q13 deletion
- Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1
- Prader-Willi syndrome due to paternal deletion of 15q11q13 type 2
- Prader-Willi syndrome due to translocation
- Schaaf-Yang syndrome
- Schuurs-Hoeijmakers syndrome
- SIM1-related Prader-Willi-like syndrome
- Smith-Magenis syndrome
Sometimes5–29%
11- 7q31microdeletion syndrome
- CNTNAP2-related developmental and epileptic encephalopathy
- CTCF-related neurodevelopmental disorder
- Floating-Harbor syndrome
- Hao-Fountain syndrome due to 16p13.2 microdeletion
- Intellectual disability-eye abnormalities-microcephaly-peripheral spasticity syndrome
- Lamb-Shaffer syndrome
- Mucopolysaccharidosis type 3
and 3 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.