Rare diseases · Sign or symptom

Abnormal periungual morphology

HP:0100803

What it means

An abnormality of the region around the nails of the fingers or toes.

The nailfold denotes the folds of skin that frame the nail plate in the periungual region.

Rare diseases that can present with this4

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Abnormality of the periungual region

Abnormal periungual morphology

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.