Rare diseases · Sign or symptom
Abnormal eyebrow morphology
Abnormality of the eyebrow
HP:0000534
What it means
An abnormality of the eyebrow.
Rare diseases that can present with this27
Very common80–99%
13- Acquired hypertrichosis lanuginosa
- Acrodermatitis enteropathica
- Acromicric dysplasia
- Deafness-enamel hypoplasia-nail defects syndrome
- German syndrome
- Leukomelanoderma-infantilism-intellectual disability-hypodontia-hypotrichosis syndrome
- Microphthalmia with limb anomalies
- Monilethrix
- Primary hypergonadotropic hypogonadism-partial alopecia syndrome
- Spondylo-ocular syndrome
- Unilateral ocular duplication
- Vogt-Koyanagi-Harada disease
- Waardenburg-Shah syndrome
Common30–79%
9- 1p36deletion syndrome
- Böök syndrome
- Juberg-Hayward syndrome
- Mandibuloacral dysplasia with type A lipodystrophy
- Peripheral demyelinating neuropathy-central dysmyelinating leukodystrophy-Waardenburg syndrome-Hirschsprung disease
- Piebald trait-neurologic defects syndrome
- Pili torti
- Schwartz-Jampel syndrome
- Waardenburg syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions, and Orphanet separately records 1 disease where this sign is specifically absent. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.