Rare diseases · Sign or symptom
Abnormal dental morphology
Abnormality of dental shape
HP:0006482
What it means
An abnormality of the morphology of the tooth.
Rare diseases that can present with this45
Very common80–99%
21- Autosomal dominant hypohidrotic ectodermal dysplasia
- CHIME syndrome
- Chondroectodermal dysplasia with night blindness
- CODAS syndrome
- Coffin-Lowry syndrome
- Craniosynostosis-anal anomalies-porokeratosis syndrome
- Dentin dysplasia
- Distal duplication 18q syndrome
- Ectodermal dysplasia, trichoodontoonychial type
- EEM syndrome
- Gingival fibromatosis-facial dysmorphism syndrome
- Hennekam syndrome
- Hypodontia-dysplasia of nails syndrome
- Hypohidrotic ectodermal dysplasia
- Infantile systemic hyalinosis
- Intellectual disability, Buenos-Aires type
- Intellectual disability-seizures-macrocephaly-obesity syndrome
- Non-eruption of teeth-maxillary hypoplasia-genu valgum syndrome
- Odonto-onycho dysplasia-alopecia syndrome
- Smith-Lemli-Opitz syndrome
- Trichodermodysplasia-dental alterations syndrome
Common30–79%
14- ADULT syndrome
- Ahmad syndrome
- Amelo-onycho-hypohidrotic syndrome
- Autosomal recessive hypohidrotic ectodermal dysplasia
- Cherubism
- Cleft lip/palate-ectodermal dysplasia syndrome
- Incontinentia pigmenti
- Kabuki syndrome
- Microcephaly-cervical spine fusion anomalies syndrome
- Microphthalmia, Lenz type
- Naegeli-Franceschetti-Jadassohn syndrome
- Oculodental syndrome, Rutherfurd type
- Thumb deformity-alopecia-pigmentation anomaly syndrome
- Williams syndrome
Sometimes5–29%
9- 17p11.2microduplication syndrome
- Cockayne syndrome
- Ectodermal dysplasia-skin fragility syndrome
- Metaphyseal chondrodysplasia, Rosenberg type
- Mowat-Wilson syndrome
- Mowat-Wilson syndrome due to a ZEB2 point mutation
- Mowat-Wilson syndrome due to monosomy 2q22
- Oligodontia
and 1 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Abnormality of dental morphology · Abnormality of shape of tooth · Abnormally shaped teeth · Deformity of teeth · Dental deformity · Dental malformations · Malformation of teeth · Malformed teeth
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.