Rare diseases · Sign or symptom
Abnormal circulating interleukin concentration
HP:0011117
What it means
The concentration of an interleukin (a class of cytokines) is outside the limits of normal.
Rare diseases that can present with this12
Very common80–99%
7- Acquired hemophagocytic lymphohistiocytosis associated with malignant disease
- Adult acute respiratory distress syndrome
- Hepatic veno-occlusive disease-immunodeficiency syndrome
- Macrophage activation syndrome
- Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency
- Sweet syndrome
- T-cell based immunotherapy-associated cytokine release syndrome
Common30–79%
4The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Abnormal serum IL level · Abnormal serum interleukin level · Abnormality of IL secretion · Abnormality of interleukin secretion
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.