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Start free with EleplanRheumatoid factor-positive polyarticular juvenile idiopathic arthritis
ORPHA:85435Disease
Also called Juvenile idiopathic rheumatoid factor-positive polyarthritis · Juvenile polyarthritis with rheumatoid factor · Rheumatoid factor-positive polyarticular JIA
What it is
A rare form of juvenile idiopathic arthritis characterized by distal and symmetrical polyarthritis (more than 5 joints) with presence of rheumatoid factor and possible evolution towards the appearance of erosions and joint destruction.
Key facts
- Prevalence
- 1-9 / 100 000 (Europe)
- Age of onset
- Childhood
- Inheritance
- Unknown
- Classified as
- Disease
Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.
Signs and symptoms
Common30–79%
11- Abnormal circulating interleukin concentration
- Abnormality of epiphysis morphology
- Abnormality of limb bone morphology
- Elevated circulating C-reactive protein concentration
- Elevated erythrocyte sedimentation rate
- Interphalangeal joint erosions
- Joint swelling
- Limitation of joint mobility
- Progressive joint destruction
- Symetrical distal arthritis
- Synovitis
These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.
ICD-10 codes
Related health topics
Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.
Cross-references
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.
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