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Z21

Billable

Asymptomatic human immunodeficiency virus [HIV] infection status

Z21 is the ICD-10-CM code for Asymptomatic human immunodeficiency virus [HIV] infection status. It is a billable, specific code valid for reimbursement.

Status
Billable
Chapter
Z00-Z99
Edition
FY2026

Z00-Z99 Factors influencing health status and contact with health services

Includes

  • •HIV positive NOS

Excludes1 — not coded here

  • •acquired immunodeficiency syndrome (B20)
  • •contact with human immunodeficiency virus [HIV] (Z20.6)
  • •exposure to human immunodeficiency virus [HIV] (Z20.6)
  • •human immunodeficiency virus [HIV] disease (B20)
  • •inconclusive laboratory evidence of human immunodeficiency virus [HIV] (R75)

Code first

  • •Human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-)

Frequently asked questions

What is ICD-10 code Z21?
Z21 is the ICD-10-CM code for "Asymptomatic human immunodeficiency virus [HIV] infection status". It falls under Z00-Z99 Factors influencing health status and contact with health services.
Is Z21 a billable code?
Yes — Z21 is a billable, specific ICD-10-CM code valid for reimbursement.
What is excluded from Z21?
Excludes1 (not coded here): acquired immunodeficiency syndrome (B20); contact with human immunodeficiency virus [HIV] (Z20.6); exposure to human immunodeficiency virus [HIV] (Z20.6); human immunodeficiency virus [HIV] disease (B20).

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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