D80

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D80

Non-billable

Immunodeficiency with predominantly antibody defects

D80 is the ICD-10-CM code for Immunodeficiency with predominantly antibody defects. It is a non-billable category code — use a more specific child code such as D80.0 for billing.

Status
Header (non-billable)
Chapter
D50-D89
Subcodes
10
Edition
FY2026

D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

What this means — in plain language

MedlinePlus · NIH

What is the immune system? Your immune system is a complex network of cells, tissues, and organs. Together they help the body fight infections and other diseases. When germs such as bacteria or viruses invade your body, they attack and multiply. This is called an infection. The infection causes the disease that makes you sick. Your immune system protects you from the disease by fighting off the germs. What are the…

Read more about Immune System and Disorders at MedlinePlus ↗

Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.

No additional coding notes for this code.

Conditions mapped to this code

MedlinePlus · NIH

Plain-language health-topic references grounded in MedlinePlus (NIH/NLM).

19 rare diseases filed under this code

Orphanet · INSERM

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. This code is shared — showing 12 of 19.

Orphadata Science: Free access data from Orphanet. © INSERM 1999. 3 of these are exact ICD-10 matches; the rest are broader-bucket mappings.

Frequently asked questions

What is ICD-10 code D80?
D80 is the ICD-10-CM code for "Immunodeficiency with predominantly antibody defects". It falls under D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.
Is D80 a billable code?
No — D80 is a non-billable header code. Use a more specific child code (such as D80.0) for billing.
What are the subcodes of D80?
D80 has 10 more specific child codes, including D80.0, D80.1, D80.2.

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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