Staphylococcal scalded skin syndrome

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Staphylococcal scalded skin syndrome

ORPHA:36236Disease

Also called Generalized exfoliative disease · SSSS

What it is

A rare staphylococcal toxemia caused by epidermolytic toxins of Staphylococcus aureus and characterized by the appearance of widespread erythematous patches, on which large blisters develop. Upon rupture of these blisters, the skin appears reddish and scalded. The lesions typically begin in the face and rapidly expand to other parts of the body. The disease may be complicated by pneumonia and sepsis. It most commonly affects newborns and infants.

Key facts

Prevalence
<1 / 1 000 000 (annual incidence, Germany)
Age of onset
All ages
Classified as
Disease

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

ICD-10 codes

L00ICD-10 names this disease exactly

Cross-references

MEDDRA 10041929MESH D013206MONDO 0018181UMLS C0038165

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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