Rare diseases · Sign or symptom
Widely-spaced maxillary central incisors
Gap between upper front teeth
HP:0001566
What it means
Increased distance between the maxillary central permanent incisor tooth.
Rare diseases that can present with this5
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Central incisor gap · Diastasis of the central incisors · Diastema between maxillary central incisors · Diastema between upper front teeth · Diastema between upper incisors · Separated superior central incisors · Wide gap between upper central incisors · Wide upper central incisors
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.