Unusual skin infection

What it means

Increased susceptibility to infection of the skin, nails, or mucous membranes, as manifested by recurrent or severe cutaneous or mucosal infection, or by skin or mucous membrane infection caused by an atypical or opportunistic organism.

Recurrent or unusual skin and mucous membrane infections are characteristic of T-cell deficiencies, phagocyte defects, and inborn errors of IL-17 immunity.

Rare diseases that can present with this5

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category