Rare diseases · Sign or symptom

Unilateral narrow palpebral fissure

HP:0007946

What it means

A fixed reduction in the vertical distance between the upper and lower eyelids with short palpebral fissures on one side only.

Rare diseases that can present with this2

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Narrow palpebral fissure, unilateral · Unequal size of opening between the eyelids

Unilateral narrow palpebral fissure

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.