Rare diseases · Sign or symptom
Underdeveloped supraorbital ridges
Flattened bony protrusion above eyes
HP:0009891
What it means
Flatness of the supraorbital portion of the frontal bones.
Rare diseases that can present with this28
Very common80–99%
8Common30–79%
12- 20q11.2microduplication syndrome
- Camptodactyly syndrome, Guadalajara type 1
- Combined immunodeficiency with facio-oculo-skeletal anomalies
- Jackson-Weiss syndrome
- Laron syndrome
- Non-syndromic bicoronal craniosynostosis
- Non-syndromic bilambdoid and sagittal craniosynostosis
- Pseudoaminopterin syndrome
- Roberts syndrome
- TARP syndrome
- Tetralogy of Fallot
- Zellweger syndrome
Sometimes5–29%
8- Alpha-thalassemia-intellectual disability syndrome linked to chromosome 16
- Antley-Bixler syndrome
- Congenital sialidosis type 2
- Distal deletion 12q syndrome
- Juvenile sialidosis type 2
- Megalocornea-intellectual disability syndrome
- Microcephaly-chorioretinopathy-lymphedema syndrome
- Proximal 16p11.2 microduplication syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Depressed supraorbital margins · Depressed supraorbital ridge · Flat supraorbital margins · Flat supraorbital ridge · Hypoplasia of supraorbital margins · Hypoplasia of the supraorbital ridges · Hypoplastic supraorbital ridges · Shallow orbital ridges
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.