Rare diseases · Sign or symptom

Type II diabetes mellitus

Noninsulin-dependent diabetes

HP:0005978

What it means

A type of diabetes mellitus initially characterized by insulin resistance and hyperinsulinemia and subsequently by glucose interolerance and hyperglycemia.

Persons with type II diabetes mellitus rarely develop ketoacidosis.

In everyday care

Most people with this sign do not have a rare disease — it appears in common conditions far more often. These general reference pages cover the same topic:

Rare diseases that can present with this54

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Diabetes mellitus type 2 · Diabetes mellitus Type II · Diabetes mellitus, noninsulin-dependent · NIDDM · NIDDM diabetes mellitus · Non-insulin dependent diabetes · Noninsulin dependent diabetes mellitus · Noninsulin-dependent diabetes mellitus

Type II diabetes mellitus

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.