Rare diseases · Sign or symptom

Tibialis anterior muscle atrophy

HP:0011399

What it means

Wasting of the tibialis anterior muscle.

The tibialis anterior muscle is located in the front of the lower leg. The shin may appear prominent because of atrophy of the tibialis anterior muscle (sharp shin sign).

Rare diseases that can present with this3

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Sharp shin sign · Tibialis anterior amyotrophy · Tibialis muscle degeneration

Tibialis anterior muscle atrophy

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.