Rare diseases · Sign or symptom

Sub-retinal pigment epithelium haemorrhage

HP:0025244

What it means

An accumulation of blood located between the retinal pigment epithelium (RPE) and Bruch membrane.

This can be associated with 'polypoidal lesions', neovascularization, or trauma.

Rare diseases that can present with this2

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Sub-RPE hemorrhage · Subretinal pigment epithelium haemorrhage · Subretinal pigment epithelium hemorrhage

Sub-retinal pigment epithelium haemorrhage

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.