Rare diseases · Sign or symptom
Small nail
Small nails
HP:0001792
What it means
A nail that is diminished in length and width, i.e., underdeveloped nail.
Rare diseases that can present with this32
Very common80–99%
4Common30–79%
13- 1q41q42microdeletion syndrome
- 20p13microdeletion syndrome
- 21q22.11q22.12microdeletion syndrome
- Acrocapitofemoral dysplasia
- Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome
- Distal deletion 15q syndrome
- Filippi syndrome
- Focal dermal hypoplasia
- Global developmental delay-alopecia-macrocephaly-facial dysmorphism-structural brain anomalies syndrome
- Isolated congenital onychodysplasia
- Simpson-Golabi-Behmel syndrome
- Trisomy 18 syndrome
- Zechi-Ceide syndrome
Sometimes5–29%
14- ALG12-CDG
- Aminopterin/methotrexate embryofetopathy
- Brachydactyly-short stature-retinitis pigmentosa syndrome
- Distal deletion 12q syndrome
- Hidrotic ectodermal dysplasia
- Hyperphosphatasia-intellectual disability syndrome
- Intellectual disability-brachydactyly-Pierre Robin syndrome
- Kagami-Ogata syndrome due to paternal uniparental disomy of chromosome 14
and 6 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Hypoplastic nail · Hypoplastic nails · Nail hypoplasia
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.