Rare diseases · Sign or symptom
Shallow orbits
Decreased depth of eye sockets
HP:0000586
What it means
Reduced depth of the orbits associated with prominent-appearing ocular globes.
Rare diseases that can present with this15
Common30–79%
8- Apert syndrome
- Arachnodactyly-abnormal ossification-intellectual disability syndrome
- Aymé-Gripp syndrome
- Hutchinson-Gilford progeria syndrome
- Isolated sedoheptulokinase deficiency
- Keppen-Lubinsky syndrome
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome
- Schinzel-Giedion syndrome
Sometimes5–29%
6- ALG9-CDG
- Megalencephaly-severe kyphoscoliosis-overgrowth syndrome
- Mucolipidosis type II
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome due to 9q21.3 microdeletion
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome due to a point mutation
- Ossification anomalies-psychomotor developmental delay syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Decreased depth of orbits · Shallow eye sockets · Small shallow orbits
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.