Rare diseases · Sign or symptom
Remnants of the hyaloid vascular system
HP:0007968
What it means
Persistence of the hyaloid artery, which is the embryonic artery that runs from the optic disc to the posterior lens capsule may persist; the site of attachment may form an opacity. The hyaloid artery is a branch of the ophthalmic artery, and usually regresses completely before birth. This features results from a failure of regression of the hyaloid vessel, which supplies the primary vitreous during embryogenesis and normally regresses in the third trimester of pregnancy, leading to a particular form of posterior cataract.
Rare diseases that can present with this6
Very common80–99%
1The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Congenital retinal septum · Persistent fetal vasculature · Persistent foetal vasculature · Persistent hyperplasia of primary vitreous · Persistent hyperplastic primary vitreous · Persistent hypertrophic primary vitreous · Persistent posterior fetal fibrovascular sheath of the lens · Persistent posterior foetal fibrovascular sheath of the lens
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.