Rare diseases · Sign or symptom

Reduced circulating catalase activity

HP:0012517

What it means

Activity or concentration of catalase in the blood circulation below the lower limit of normal.

Catalase catalyzes the decomposition of hydrogen peroxide to water and oxygen.

Rare diseases that can present with this1

Very common80–99%

1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Reduced catalase level

Reduced circulating catalase activity

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.