Rare diseases · Sign or symptom
Pericardial effusion
Fluid around heart
HP:0001698
What it means
Accumulation of fluid within the pericardium.
Rare diseases that can present with this33
Common30–79%
8Sometimes5–29%
18- Acute interstitial pneumonia
- Aymé-Gripp syndrome
- Chédiak-Higashi syndrome
- Classical-like Ehlers-Danlos syndrome type 2
- Congenital enterovirus infection
- Congenital heart block
- Congenital tricuspid valve dysplasia
- Familial dilated cardiomyopathy with conduction defect due to LMNA mutation
and 10 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Pericardial effusions
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.