Rare diseases · Sign or symptom

Patchy osteosclerosis

Uneven increase in bone density

HP:0005686

What it means

Patchy (irregular) increase in bone density. This can take on many forms depending on severity and distribution as can be seen on x-rays.

Rare diseases that can present with this1

Sometimes5–29%

1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Increased bone mineral densityPatchy changes of bone mineral density

Also called: Patchy increase of bone mineral density

Patchy osteosclerosis

Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.

Start free with Eleplan

This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.