Rare diseases · Sign or symptom
Osteosclerosis of the base of the skull
HP:0005746
What it means
An increase in bone density affecting the basicranium (base of the skull).
Bundled term. Consider obsoleting it and splitting of osteosclerosis of base of skull.
Rare diseases that can present with this2
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Osteosclerosis of the skull base
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.