Rare diseases · Sign or symptom
Oral mucosal blisters
Blisters of mouth
HP:0200097
What it means
Blisters arising in the mouth.
Rare diseases that can present with this23
Very common80–99%
6Common30–79%
9- Autosomal dominant generalized epidermolysis bullosa simplex, severe form
- Autosomal recessive generalized epidermolysis bullosa simplex
- Epidermolysis bullosa simplex with pyloric atresia
- IgA pemphigus
- Laryngo-onycho-cutaneous syndrome
- Pemphigus vegetans
- Recessive dystrophic epidermolysis bullosa inversa
- Self-improving dystrophic epidermolysis bullosa
- Stevens-Johnson syndrome/toxic epidermal necrolysis spectrum
Sometimes5–29%
7- Autosomal dominant generalized dystrophic epidermolysis bullosa
- Autosomal dominant generalized epidermolysis bullosa simplex, intermediate form
- Bullous pemphigoid
- Epidermolysis bullosa simplex with mottled pigmentation
- Junctional epidermolysis bullosa inversa
- Late-onset junctional epidermolysis bullosa
- Localized dystrophic epidermolysis bullosa, pretibial form
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions, and Orphanet separately records 1 disease where this sign is specifically absent. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Blebs of oral mucosa · Bullae of oral mucosa · Oral blistering · Oral mucosa blisters
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.