Rare diseases · Sign or symptom

Open angle glaucoma

HP:0012108

What it means

A type of glaucoma defined by an open, normal appearing anterior chamber angle and raised intraocular pressure,

Evidence of optic nerve damage can include s optic disc abnormalities (Vertical cup:disk ratio over the 97. 5th percentile in the normal population), visual field defects. The role of increased intraocular pressure (IOP) in glaucoma is debated, but an IOP exceeding the 99. 5th percentile of the normal population may be considered to support the diagnosis.

Rare diseases that can present with this5

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Primary open angle glaucoma

Open angle glaucoma

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.