Rare diseases · Sign or symptom
Neonatal epiphyseal stippling
Speckled calcifications in bone end parts in neonates
HP:0005756
What it means
The presence of abnormal punctate (speckled, dot-like) calcifications in one or more epiphyses during the neonatal period.
Rare diseases that can present with this1
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Epiphyseal stippling in neonates
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.