Rare diseases · Sign or symptom

Multifocal hyperintensity of cerebral white matter on MRI

HP:0040329

What it means

An abnormal area of increased brightness (hyperintensity) that occurs in several distinct areas.

Rare diseases that can present with this3

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Multifocal hyperintensity of cerebral…

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.