Rare diseases · Sign or symptom

Metabolic ketoacidosis

HP:0005979

What it means

A metabolic acidosis due to accumulation of ketone bodies generally observed in the setting of poor nutritional intake.

Rare diseases that can present with this2

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Starvation ketoacidosis

Metabolic ketoacidosis

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.