Low maternal circulating chorionic gonadotropin concentration

What it means

An abnormally low concentration of maternal serum human chorionic gonadotropin as compared to normal values for gestational-age.

Reduced levels of alpha-fetoprotein can be seen in some fetal disorders such as Down syndrome.

Rare diseases that can present with this1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Low maternal serum chorionic gonadotropin · Low maternal serum hCG