Rare diseases · Sign or symptom
Long eyelashes
Increased length of eyelashes
HP:0000527
What it means
Mid upper eyelash length >10 mm or increased length of the eyelashes (subjective).
Measurement should be done on the longest lashes, which are usually at the center of the lid. Normal values are 7.99 - 1.05 mm in boys and 7.76 - 1.03 mm in girls. Note that Eyelash trichomegaly is defined as increase in length (12 mm or more), curling, pigmentation or thickness of eyelashes.
Rare diseases that can present with this48
Very common80–99%
10- 2p21microdeletion syndrome
- Acromicric dysplasia
- Cantú syndrome
- Cognitive impairment-coarse facies-heart defects-obesity-pulmonary involvement-short stature-skeletal dysplasia syndrome
- Cohen syndrome
- Cornelia de Lange syndrome
- Craniodigital-intellectual disability syndrome
- Kabuki syndrome
- Microtriplication 11q24.1 syndrome
- Short stature-wormian bones-dextrocardia syndrome
Common30–79%
20- 2p15p16.1microdeletion syndrome
- 2q23.1microduplication syndrome
- 7q11.23microduplication syndrome
- Acrocardiofacial syndrome
- Aphonia-deafness-retinal dystrophy-bifid halluces-intellectual disability syndrome
- Autosomal dominant Robinow syndrome
- Autosomal recessive Robinow syndrome
- CTCF-related neurodevelopmental disorder
- Early-onset seizures-distal limb anomalies-facial dysmorphism-global developmental delay syndrome
- Menke-Hennekam syndrome
- MOGS-CDG
- Nicolaides-Baraitser syndrome
- Pachydermoperiostosis
- Phelan-McDermid syndrome
- Pontocerebellar hypoplasia type 10
- Schuurs-Hoeijmakers syndrome
- Severe intellectual disability-corpus callosum agenesis-facial dysmorphism-cerebellar ataxia syndrome
- Temple-Baraitser syndrome
- Trichomegaly-retina pigmentary degeneration-dwarfism syndrome
- Wiedemann-Steiner syndrome
Sometimes5–29%
16- 17q23.1q23.2microdeletion syndrome
- 19p13.13microdeletion syndrome
- 4q21microdeletion syndrome
- 8q24.3microdeletion syndrome
- Aymé-Gripp syndrome
- Cerebello-oculo-facio-genital syndrome
- Dihydropyrimidine dehydrogenase deficiency
- Early-onset epileptic encephalopathy-cortical blindness-intellectual disability-facial dysmorphism syndrome
and 8 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Ciliary trichomegaly · Eyelash trichomegaly · Unusually long eyelashes
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.