Rare diseases · Sign or symptom

Increased muscle lipid content

Fat accumulation in muscle fibers

HP:0009058

What it means

An abnormal accumulation of lipids in skeletal muscle.

Increased neutral lipid content may be observed on muscle biopsies specimen with the specific staining of Sudan black or oil red O techniques by optic microscopy.

Rare diseases that can present with this8

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Fat accumulation in muscle fibres · Fat deposits in muscle fibers · Fat deposits in muscle fibres · Lipid accumulation in skeletal muscle · Muscle lipidosis · Skeletal muscle lipid accumulation

Increased muscle lipid content

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.