Rare diseases · Sign or symptom

Increased mean corpuscular hemoglobin concentration

HP:0025548

What it means

An elevation over the normal range of the average amount of hemoglobin per red blood cell (27 to 31 picograms/cell).

Rare diseases that can present with this3

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Increased MCH · Increased MCHC · Increased mean corpuscular haemoglobin · Increased mean corpuscular haemoglobin concentration · Increased mean corpuscular Hb concentration

Increased mean corpuscular hemoglobin…

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.