Rare diseases · Sign or symptom
Increased circulating pyruvate concentration
HP:0003542
What it means
The concentration of pyruvate in the blood circulation is above the upper limit of normal.
An abnormal increase in the concentration of pyruvate in the blood. Pyruvate is involved in energy metabolism, forming part of glycolysis and the citric acid cycle.
Rare diseases that can present with this9
Very common80–99%
2Common30–79%
5The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Increased serum pyruvate · Increased serum pyruvic acid
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.