Rare diseases · Sign or symptom
Inappropriate crying
HP:0030215
What it means
Uncontrolled episodes of crying occur without any apparent motivating stimuli.
Rare diseases that can present with this15
Very common80–99%
3Common30–79%
5Sometimes5–29%
7- 21q22.11q22.12microdeletion syndrome
- 3-phosphoglycerate dehydrogenase deficiency, infantile/juvenile form
- ALG9-CDG
- Atypical Rett syndrome
- Choanal atresia
- Multiple mitochondrial dysfunctions syndrome type 5
- Severe intellectual disability-progressive postnatal microcephaly-midline stereotypic hand movements syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Cry frequently for no reason · Cry frequently without apparent cause · Cry frequently without cause · Cry frequently without reason · Frequently cries for no reason · Frequently cries without apparent cause · Frequently cries without cause · Frequently cries without reason
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.