Rare diseases · Sign or symptom

Hypoplasia of the premaxilla

Hypoplasia of the primary palate bone

HP:0010650

What it means

An abnormality of the premaxilla (the embryonic structure that forms the anterior part of the maxilla) causing it to appear relatively small in size compared to the other parts of the maxilla or other facial structures.

Rare diseases that can present with this4

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Decreased size of premaxilla · Decreased size of the primary palate bone · Hypoplasia of the intermaxillary bone · Premaxillary bone deficiency · Premaxillary bone retrusion · Premaxillary retrusion · Premaxillary underdevelopment · Primary palate bone deficiency

Hypoplasia of the premaxilla

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.