Rare diseases · Sign or symptom

Hyperglycinuria

High urine glycine levels

HP:0003108

What it means

An increased concentration of glycine in the urine.

Normal urinary glycine total (free and combined form) excretion is around 450 mg per 24 hours.

Rare diseases that can present with this4

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Glycinuria

Hyperglycinuria

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.